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Controlled Drug Release from Loratadine-Loaded Pectin Film Dosage Forms

  Abstract   Film Dosage forms [FD] prepared using water-soluble polysaccharides swell and transform into a gelatinous substance in an aqueous medium. In this study, we prepared FDs using pectin as the film base and modified them using additives such as chitosan. We then incorporated loratadine, an anti-allergic agent, into the FDs and investigated the film disintegration and drug dissolution profiles in a limited volume of aqueous medium. The FD swelled when it came in contact with physiological saline, leading to disintegration. The film disintegration rate decreased with increasing pectin concentration. However, the drug dissolution rate was not affected by the disintegration profile. The addition of chitosan to the film base decreased the drug dissolution rate, although the disintegration rate of the FD scarcely changed. Modifying the FD by adding chitin to the film base did not influence the drug dissolution rate. When the FD was soaked in artificial gastric juice, lorata...

Dimensions and Indicators for Sustainable Construction Materials: A Review- Crimson Publishers

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  Dimensions and Indicators for Sustainable Construction Materials: A Review by Humphrey Danso* in Crimson Publishers: Peer Reviewed Material Science Journals       Sustainable construction practices are provided to reduce resource depletion and prevent environmental degradation caused by construction activities and products. The purpose of this paper is to review the general and relevant available indicators for measuring sustainable construction materials. The paper outlines the main idea behind sustainability assessment. It also reviews the critical sustainability indicators which are grouped under the 3Es, thus environmental, social equity and economic dimensions. Furthermore, it highlights the analytical hierarchical process in sustainable construction materials assessment. The paper concludes that it is important to identify the relevant sustainable indicators for construction materials and be able to measure the indicators following the analytical hierar...